Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
USERS' SCORE
Moderately Good
Based on 21 Reviews
7.8
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Thiamin (B1 from culture of S.cerevisiae)
5 mg
417%
Riboflavin (B2 from culture of S. cerevisiae)
10 mg 
769%
Niacin (as Niacinamide from culture of S. cerevisiae)
45 mg 
281%
Vitamin B6 (from culture of S. cerevisiae)
10 mg 
588%
Folate (from culture of S. cerevisiae)
450 mcg DFE
113%
Vitamin B12 (as Methylcobalamin from culture of S. cerevisiae)
133 mcg 
5542%
Biotin (from culture of S. cerevisiae)
325 mcg 
1083%
Pantothenic Acid (from culture of S. cerevisiae)
45 mg
900%
RAW Organic Fruit & Vegetable Blend
360 mg
+
RAW Probiotic & Enzyme Blend
60 mg
+

Top Medical Research Studies

9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Read More
8
Methylcobalamin shows promising effectiveness
This study evaluated the effects of intramuscular methylcobalamin injections on chronic low back pain.

In a rigorously designed double-blinded, randomized controlled trial, 60 patients were divided into treatment and placebo groups.

We observed significant improvements in pain and disability scores among those receiving methylcobalamin compared to the placebo.

Additionally, the treatment was found to be safe, with only minor side effects reported.
Read More
8
Vitamin B complex aids back pain relief
We examined how well celecoxib and a combined vitamin B complex worked for people experiencing lower back pain, comparing them with meloxicam.

Our findings indicated that celecoxib, especially when paired with Neuromultivit (a vitamin B complex), showed improved effectiveness in relieving both acute and chronic back pain.

Interestingly, while meloxicam offered similar initial pain relief, celecoxib was found to be superior for long-term recovery and quality of life improvements.

This suggests that adding vitamin B to treatment could enhance outcomes for those suffering from chronic lower back pain.
Read More

Most Useful Reviews

9
Pain alleviation
9 people found this helpful
Stunning vitamins! After childbirth, I suffered back pain for three years with no relief. Since taking these vitamins, I feel invigorated and my work capacity has greatly improved. However, once I stop, the pain returns.
Read More
9
Hair restoration
6 people found this helpful
This high-quality product, made from natural ingredients, has really helped me. My doctor recommended it during a time of severe hair loss, and thankfully, my hair has stopped falling out. Moreover, I’m no longer experiencing back pain. This will be my second order. Thank you, iHerb!
Read More
9
More energy
5 people found this helpful
I’ve been taking these vitamins in 2-3 month courses for the second time. My back pain has disappeared, and I feel more energetic and positive. I’m eager to engage in sports now, and my hair is growing better too! This is the best natural B complex on iHerb.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
  • All Researches
9
Combination therapy shows effectiveness
We set out to explore whether a rehabilitation program combined with specific supplements could effectively treat sciatica in young patients. Our study involved 128 individuals who were divided into three groups: one receiving both rehabilitation and supplements, one only with rehabilitation, and one with only supplements.

After treatment, the group with both rehabilitation and supplements showed significant improvement in pain relief and overall quality of life compared to the others. While the supplement-only group didn’t perform as well, this combination approach proved beneficial, particularly in reducing pain and enhancing stability.
Read More
We explored how effective vitamin B complex, alongside nonsteroidal anti-inflammatory drugs, is in treating back pain. Our study involved 70 patients divided into two groups, one receiving a vitamin B complex blend and the other a different pain relief combination.

Both groups showed improvement, but the first group experienced a clearer reduction in pain levels over time. By the third visit, they reported significantly less discomfort compared to the second group. Though both treatments were effective, the vitamin B complex showed a more pronounced impact on pain relief and patient satisfaction.
Read More
9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Read More
9
Vitamin B complex effective for pain
We examined how Dolo-Neurobion, a blend of essential B vitamins and an analgesic, affects acute lumbosacral pain. In a study of 53 patients, we found that this treatment yielded good to excellent results in 77.4% of cases, while 15.1% experienced moderate effects. The approach combined initial parenteral dosing with continuation through oral intake, and any necessary antibiotics were also used. Most notably, we observed no significant side effects, making Dolo-Neurobion a promising option for back pain relief linked to pelvic organ issues.
Read More
8
Vitamin B12 aids postoperative recovery
We explored how combining dexamethasone with vitamin B12 could impact early recovery from back and leg pain after a specific spine surgery called percutaneous endoscopic interlaminar discectomy (PEID).

In our study, patients were divided into two groups: one received only the surgery, while the other got epidural injections of both medications during surgery.

Results showed that the combined treatment significantly reduced pain and inflammation, leading to better early recovery outcomes. This suggests that using this combination might be a great option for patients undergoing this type of surgery.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 21 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Pain alleviation
9 people found this helpful
Stunning vitamins! After childbirth, I suffered back pain for three years with no relief. Since taking these vitamins, I feel invigorated and my work capacity has greatly improved. However, once I stop, the pain returns.
Read More
9
Hair restoration
6 people found this helpful
This high-quality product, made from natural ingredients, has really helped me. My doctor recommended it during a time of severe hair loss, and thankfully, my hair has stopped falling out. Moreover, I’m no longer experiencing back pain. This will be my second order. Thank you, iHerb!
Read More
9
More energy
5 people found this helpful
I’ve been taking these vitamins in 2-3 month courses for the second time. My back pain has disappeared, and I feel more energetic and positive. I’m eager to engage in sports now, and my hair is growing better too! This is the best natural B complex on iHerb.
Read More
9
Muscle pain
3 people found this helpful
This is my favourite! I buy multiple cans and only take these for muscle pain and overall nervous system support. A course of this product yields great results when it’s needed.
Read More
9
Magical vitamins
2 people found this helpful
I was apprehensive about taking vitamin B due to potential side effects, but these are remarkable. They alleviate back pain and stress remarkably well. I recommend them to everyone; their benefits are clear.
Read More

Frequently Asked Questions

7.5
Back relief
10 people found this helpful
I’m unsure about the overdose norms for vitamin content, but I carefully take one capsule and my back feels better within a week.
9
More energy
5 people found this helpful
I’ve been taking these vitamins in 2-3 month courses for the second time. My back pain has disappeared, and I feel more energetic and positive. I’m eager to engage in sports now, and my hair is growing better too! This is the best natural B complex on iHerb.
8
Pain reduction
3 people found this helpful
I have benefited greatly from this product. I was suffering from muscle and bone pain, alongside lethargy. After three months of use, I started noticing a difference. Give it a month off before resuming.
6
Supportive effect
3 people found this helpful
My husband and I have been using these vitamins for the second year and have had stable good results. We maintained our regimen during COVID. They help with back pain, fatigue, and overall well-being, although we sometimes need to supplement with others for better results.
9
Effective for sciatica
1 people found this helpful
I dealt with sciatica and after injections, my doctor suggested a course of vitamin B. This complex was natural and highly effective. My back pain disappeared completely, and I felt more relaxed.
9
Pain alleviation
9 people found this helpful
Stunning vitamins! After childbirth, I suffered back pain for three years with no relief. Since taking these vitamins, I feel invigorated and my work capacity has greatly improved. However, once I stop, the pain returns.
7.5
Muscle pain help
A decent complex with non-therapeutic dosages; it aids with muscle and back pain. It's easy to digest with a recommended dosage of two per day.
We analyzed a study that looked at how B vitamins—B1, B6, and B12—work alongside diclofenac to help relieve back pain in people suffering from acute lumbago.

In a randomized, double-blind trial, participants received either diclofenac plus B vitamins or diclofenac alone. After three days, those taking the combination therapy reported significantly better pain relief and mobility than those on diclofenac only.

Despite the encouraging results, we noted that the study recorded pain measurements only until participants withdrew, which could impact the findings.
8
Vitamin B aids back pain relief
We examined how vitamin B complex affects back pain by comparing two treatments: diclofenac alone versus diclofenac with B vitamins. In our randomized double-blind study with 123 participants suffering from acute lumbar pain, we found that those using B vitamins alongside diclofenac experienced better pain relief.

Notably, 30 patients in the combination group could stop treatment early due to symptom relief, compared to just 15 in the diclofenac-only group. This suggests that B vitamins not only improve outcomes but may also help reduce reliance on anti-inflammatory medications.
9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
8
Methylcobalamin shows promising effectiveness
This study evaluated the effects of intramuscular methylcobalamin injections on chronic low back pain.

In a rigorously designed double-blinded, randomized controlled trial, 60 patients were divided into treatment and placebo groups.

We observed significant improvements in pain and disability scores among those receiving methylcobalamin compared to the placebo.

Additionally, the treatment was found to be safe, with only minor side effects reported.

References

  1. He C, Li J, Hu W, Xiao B, Fan T, et al. Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial. J Orthop Surg Res. 2024;19:733. doi:10.1186/s13018-024-05210-z
  2. Scaturro D, Vitagliani F, Tomasello S, Sconza C, Respizzi S, et al. Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial. Medicina (Kaunas). 2023;59. doi:10.3390/medicina59122197
  3. Antonen EG, Kruchek MM, Nikitina MV. [Evaluation of the effectiveness of treatment of patients with nonspecific pain syndrome in the lower back with celecoxib and a combined preparation of B vitamins]. Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122:65. doi:10.17116/jnevro202212208165
  4. Barantsevich ER, Yakovlev AA, Gavrilova EA, Gavrichenko AV, Pushkarev MS, et al. [Study of the clinical efficacy and safety of the scheme of step therapy of nonsteroidal anti-inflammatory drugs and a complex of B vitamins in patients with low back pain]. Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121:67. doi:10.17116/jnevro202112110167
  5. Nava-Mesa MO, Aispuru Lanche GR. [Role of B vitamins, thiamine, pyridoxine, and cyanocobalamin in back pain and other musculoskeletal conditions: a narrative review]. Semergen. 2021;47:551. doi:10.1016/j.semerg.2021.01.010
  6. Calderon-Ospina CA, Nava-Mesa MO, Arbeláez Ariza CE. Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis. Pain Med. 2020;21:766. doi:10.1093/pm/pnz216
  7. Khabirov FA, Khaibullin TI, Granatov EV. [Evaluation of efficiency and safety of adding neuromultivit to basic therapy of vertebrogenic radiculopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117:38. doi:10.17116/jnevro201711710138-43
  8. Chiu CK, Low TH, Tey YS, Singh VA, Shong HK. The efficacy and safety of intramuscular injections of methylcobalamin in patients with chronic nonspecific low back pain: a randomised controlled trial. Singapore Med J. 2011;52:868.
  9. Levin OS, Moseĭkin IA. [Vitamin B complex (milgamma) in the treatment of vertebrogenic lumbosacral radiculopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2009;109:30.
  10. Mibielli MA, Geller M, Cohen JC, Goldberg SG, Cohen MT, et al. Diclofenac plus B vitamins versus diclofenac monotherapy in lumbago: the DOLOR study. Curr Med Res Opin. 2009;25:2589. doi:10.3111/13696990903246911
  11. Mauro GL, Martorana U, Cataldo P, Brancato G, Letizia G. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci. 2000;4:53.
  12. Brüggemann G, Koehler CO, Koch EM. [Results of a double-blind study of diclofenac + vitamin B1, B6, B12 versus diclofenac in patients with acute pain of the lumbar vertebrae. A multicenter study]. Klin Wochenschr. 1990;68:116.
  13. Kuhlwein A, Meyer HJ, Koehler CO. [Reduced diclofenac administration by B vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus B vitamins) in acute lumbar vertebral syndromes]. Klin Wochenschr. 1990;68:107.
  14. Kunt T. [Complaints in the lumbosacral region and their management with Dolo-Neurobion]. Fortschr Med. 1978;96:299.
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